Quick and Easy Mexican Pork Tenderloin

Pork tenderloin is one of the best cuts of meat to work with. Not only is this hearty and lean cut of pork healthy and easy to prepare, but it also can be seasoned and flavored with basically any style that you like!

Spicing pork tenderloin with Mexican flavors is one of the best options. Do you want to learn how to make it? Here’s your guide!


  • One 1-pound pork tenderloin
  • ¼ cup orange juice
  • 2 tablespoons Cholula hot sauce
  • 1 ½ tablespoons olive oil
  • 2 teaspoons garlic powder
  • 2 teaspoons paprika
  • 1 teaspoon cumin
  • 1 teaspoon black pepper

Start off by placing the pork tenderloin and all of the rest of the ingredients in a plastic bag and mixing them thoroughly until a marinade is formed. You’ll want to place this inside of your refrigerator and marinate for approximately 4-6 hours.

Once the marination process is finished, preheat your oven to 450 degrees F. 

While the oven is preheating, remove the marinated pork tenderloin from the bag and place into a large skillet on your stove on medium-high heat. Cook evenly on all sides for 3-4 minutes, or until the exterior of the tenderloin is browned.

Finally, place the tenderloin on an oven sheet and cook in the oven for 10-12 minutes, or until the internal temperature of the meat has reached 145 degrees F. Allow to rest for 10 minutes before serving.